For Patients
Medical Disclaimer
For Patients

What is Major Depressive Disorder (MDD)?

Understanding depression beyond the “chemical imbalance” theory—exploring brain plasticity, innovative treatments, and the path to healing.

Major Depressive Disorder (MDD) — commonly simply called depression — is a serious mental health condition characterized by a persistently low mood, loss of interest or pleasure in activities, and a range of emotional and physical symptoms…

Moving Beyond a “Chemical Imbalance” – Depression and Brain Plasticity

Brain plasticity illustration

Think of your brain like a dense network of roads and pathways. In a healthy, adaptable brain, traffic can be rerouted and new roads can be built when needed: this is neuroplasticity at work…

Rethinking Treatment: Restoring the Brain’s Flexibility

At Syntropic, we are rethinking the way depression is treated. Rather than simply trying to suppress symptoms, our approach targets the brain’s loss of plasticity…

Frequently Asked Questions (FAQ)

I thought depression was all about serotonin – a chemical imbalance. Is it not?
It’s true that serotonin and other brain chemicals are involved, but neuroplasticity plays a major role too…
Does this new treatment mean I should stop taking my antidepressant medications?
No — please don’t stop your medications unless your doctor tells you to. Our technology is still in the clinical phase…
Where can I buy a Haven device?
The Haven device isn’t available for purchase yet. It will be for sale after regulatory approval…
Are there any clinical trials I can join to try this treatment?
At the moment we’re not enrolling new participants; we’ll announce future trials on our website/newsletter…

Support and Resources

ADAA (Anxiety & Depression Association of America)

USA

Provides education, resources, and support groups for anxiety and depression.

Visit adaa.org

NAMI (National Alliance on Mental Illness)

USA

Offers education, advocacy, and support for individuals and families affected by mental illness.

Visit nami.org

ABRATA

Brazil

Brazilian non‑profit supporting people with depression and bipolar disorder (site in Portuguese).

Visit abrata.org.br

Pro Mente Austria

Austria

Umbrella organization for mental health services in Austria, with information and support (German).

Visit promenteaustria.at

Aware

Ireland

National organization supporting people with depression and bipolar disorder, plus their loved ones.

Visit aware.ie
🔔
Crisis Support
If you’re in crisis or having thoughts of harming yourself, seek help immediately. (In the US, dial 988 for the Suicide & Crisis Lifeline.)
At Syntropic, we believe in a future where depression is treated more effectively and compassionately, by working with the brain’s natural ability to heal…